Sam: So, Mel Gibson really took a turn this past year, huh?
Dean: Or he's possessed. Seriously. Think about it.

My Spidey senses are tingling.

Dean: And how would you characterize their relationship?
Girl: Relationship? No, no, they weren't having a relationship.
Dean: Just the tone or the nature of their conversation.
Girl: Well... loud. And athletic?

Dean: So he came by here?
Girl: Oh, he came by a few times.
Dean: Did he? To uh speak to Nicole?
Girl: Right.

Dean: One of Dad's rules? You never use the same crapper twice.
Sam: Everyone uses the same crapper twice.
Dean: Not us. You know what I mean.

What was that? I think she just cougar-eyed you.

I'm going to go hit the poop deck.

Whoa, this one's got a little bit of a wild side. It's all in the eyes, Sam. See it?

I'm sending death a damn fruit basket!

What was I suppose to do? Let T-1000 walk around and hope that he doesn't open fire?

I think it just goes to show that being easy is pretty much all upside.

Sam: Why don't you cut to the chase and just roll in it?
Dean: I rarely have wealth.

Supernatural Quotes

You're wrong. I am utterly indifferent to sexual orientation. On the other hand, I cannot abide hypocrites like you, Reverend. Tell your flock where your genitals have been before you speak for me.

Castiel

Do you ever get tired of urinating? I'll never get used to it.

Castiel