Homer: See, Lisa, looks like tomorrow I'll be shoveling ten feet of global warming.
Lisa: Global warming can cause weather at both extremes, hot and cold.
Homer: I see, so you're saying warming makes it colder. Well aren't you the queen of crazy land. Everything the's opposite of everything.

Kent: Homer, organised labor has been called a lumbering dinosaur.
Homer: AAAAHH!
Kent: Um, my director is asking me not to talk to you anymore.
Homer: Woohoo!

Masseuses - half doctors, half hookers that solve everything.

Moe: Pretty much if it moves, you can bet on it.
Homer: What about the Detroit Lions?
Moe: Hey, lay off Detroit. Them people is livin' in Mad Max times.

My lifestyle is my retirement plan.

They don't call me "Springfield Fats" just because I'm morbidly obese!

Oh, fudge. That's...broken. Fiddle dee dee. That will require a tetanus shot. I'm not going to swear, but I am going to...kick this dog house down!
Homer goes into a rage.)

</i> Homer

If I wanted to pay for commercials I can't skip, I'd sign up for Hulu Plus.

Son, a woman is a lot like a... a refrigerator! They're about six feet tall, 300 pounds. They make ice, and um Oh, wait a minute! Actually, a woman is more like a beer. They smell good, they look good, you'd step over your own mother just to get one! But you can't stop at one, you wanna drink another woman!

Ahh, a sand horse, car of the desert.

Marge: A lot of people sound like Sideshow Bob. Like Frasier on Cheers.
Homer: Or Frasier on Fraiser.
Marge: Or Lt. Cmdr. Tom Dodge in Down Periscope.

If Jesus had a gun, he'd be alive today.

The Simpsons Quotes

Homer: (Wearing glasses) The sum of the square roots of any two sides of an isosceles triangle is equal to the square root of the remaining side!
Man: (From inside a bathroom stall.) That's a right triangle, you idiot!
Homer: D'oh!

Wow, now I see why they call you Miss Hoover. You must have been vacuuming for an hour.

Bart