Homer: See, Lisa, looks like tomorrow I'll be shoveling ten feet of global warming.
Lisa: Global warming can cause weather at both extremes, hot and cold.
Homer: I see, so you're saying warming makes it colder. Well aren't you the queen of crazy land. Everything the's opposite of everything.

Kent: Homer, organised labor has been called a lumbering dinosaur.
Homer: AAAAHH!
Kent: Um, my director is asking me not to talk to you anymore.
Homer: Woohoo!

Masseuses - half doctors, half hookers that solve everything.

Moe: Pretty much if it moves, you can bet on it.
Homer: What about the Detroit Lions?
Moe: Hey, lay off Detroit. Them people is livin' in Mad Max times.

My lifestyle is my retirement plan.

Oh, fudge. That's...broken. Fiddle dee dee. That will require a tetanus shot. I'm not going to swear, but I am going to...kick this dog house down!
Homer goes into a rage.)

</i> Homer

If I wanted to pay for commercials I can't skip, I'd sign up for Hulu Plus.

They don't call me "Springfield Fats" just because I'm morbidly obese!

Ahh, a sand horse, car of the desert.

Son, a woman is a lot like a... a refrigerator! They're about six feet tall, 300 pounds. They make ice, and um Oh, wait a minute! Actually, a woman is more like a beer. They smell good, they look good, you'd step over your own mother just to get one! But you can't stop at one, you wanna drink another woman!

Marge: A lot of people sound like Sideshow Bob. Like Frasier on Cheers.
Homer: Or Frasier on Fraiser.
Marge: Or Lt. Cmdr. Tom Dodge in Down Periscope.

Texan: Look at all them stars How many do you think there are?
Homer: Two.

The Simpsons Quotes

Sir, I got carsick in your office.

Ralph

Mr. Burns: (reading Homer's letter) "Dear Mr. Burns. I'm so glad you enjoyed my son's blood, and your card was just great." Why Simpson, you've made my day, you're a true gentlemen.
Homer: Well I-
Mr. Burns: Hello, there's more. (continues reading) "In case you can't tell, I'm being sarcastic. You stink! You are a senile bucktoothed old mummy with bony girl arms and you smell like an elephant's butt!"