Hit it, Mr. Wizard.

Sam: Dean, enough!
Dean: What?
Sam: You just punched a Cupid!
Dean: I punched a dick!

Dean: You know I finally get why you and dad butted heads so much. You two are practically the same person. I mean I worshipped the guy, y'know: I dressed like him, I acted like him, I listened to the same music. But you are more like him than I will ever be. I see that now.
Sam: I'll take that as a compliment.
Dean: You can take it any way you want.

Dean: Let me get this straight. Your, uh, ultimate hero was not only a short man in diapers, but he was a fruitarian.
Sam: That's not the point.
Dean: That is good. Even for you, that is good

Sam: Wow, it's like a magic museum.
Dean: You must be in heaven.

Sam: It was you on the police scanner, right? This is a trick.
Trickster: Hello? Trickster.

Dean: Where am I going?
Sam: Dean, it's Valentine Day. Your favorite holiday, remember? I mean, what do you always call it - uh, Unattached Drifter Christmas?

Ever since I came back, I am a better hunter then I've ever been! Nothing scares me anymore, because I can't feel it. I don't know what's wrong with me. I think I need help.

Sam: Why shack up with a family? Is it a kinky thing? Do you like to play with your food? Roll over, Lucky. Speak.
Lucky: Go to hell.
Sam: Already been. Didn't agree with me.

Dean: You're gonna go out there again?
Sam: Well, crap doesn't hit the fan with coffee breaks.

Dean: What exactly are we gonna march up there and tell 'em?
Sam: Uh, the truth.
Dean: What, that their sons are back from the future to save them from an angel gone Terminator? Come on, those movies haven't even come out yet.

Dean: What a douchebag.
Sam: That's Jeb Dexter.
Dean: I don't even want to know how you know that.
Sam: He's famous, kind of.
Dean: For what, douchebaggery?

Supernatural Quotes

Why do they call this place The Empty? It's full. It's full of sorrow and despair playing over and over again of angels and demons dreaming about their regrets. Forever.

Ruby

Weird, creepy, off-the-grid "Children of the Corn" people? Yeah, I’m in.

Dean