Penny: Next time I get pulled over for a speeding ticket, here come the waterworks.
Sheldon [running to bathroom]: Here come the waterworks!
Leonard: Aren't you gonna ask?
Penny: What is this, my first day?

Sheldon: Boy, do I have to urinate.
Leonard: If only there were a solution
to that.
Sheldon: Seriously. I feel like I've got
a fish tank in my pelvis.

Sheldon: ... now you're going to need a stronger friend named latex.
Mrs. Cooper: Are you having the sex talk with me?
Sheldon: Well someone has to.
Mrs. Cooper: Oh, dear Lord!
Sheldon: Yeah, well... No, don't look at him, he's mad at you right now.

Sheldon: Then why are you doing it?
Mrs. Cooper: Because I'm not perfect, Shelly. And that man's booty is.

I love my mother. Even if she fornicates like a demonic weasel.

Apparently any man is welcome in his house, why not you?

Sheldon: Can you recommend a surface you haven't had coitus on?
Mrs. Cooper: That's not funny. Maybe we should sit at the table.

Mrs. Cooper: Shelly! I'm so glad you're here!
Sheldon: I saw you having naked sex.

I used to live in those genitals. And if someone wants to move into my old room, I should at least get a vote.

Sheldon: Do you have any idea what it's like to see your mother ravaging someone?
Howard: Does a brisket count?

I saw my mommy with a naked man and she was trying to be a mommy again.

Howard: Should we stop holding hands now?
Sheldon: In a minute.
Howard: Okay, good.

TBBT Quotes

Penny: Here's a question-- as an alien pretending to be human, are you planning to engage in any post-prom mating rituals with Amy?
Sheldon: There are post-prom mating rituals?
Penny: Not always. Unless your date drives a van with an air mattress, then always.
Sheldon: Well, if it's part of the prom experience, then I'm open to it.
Penny: You're kidding.
Sheldon: I may be an alien, but I have urges.If Amy wants to copulate by firing her eggs into space, well, then, I will happily catch them with the reproductive sac on my upper flermin. I'm not the best at reading facial cues, but I can see that you're a little turned on.

Raj: Well, to paraphrase Shakespeare: It's better to have loved and lost than to stay home every night and download increasingly shameful pornography.
Penny: Oh... you poor baby.
Raj: What's wrong with me, Penny?
Penny: Nothing, nothing. You know, if we weren't friends - and you hadn't brought up that creepy pornography story - I'd be on you like the speed of light squared on matter to make energy.
Raj: Hey, you totally got that right. E = MC squared.
Penny: I listen. I have no idea what it means, but I listen.