Leonard: All right. I officially reinstate Anything Can Happen Thursday.
Penny: Great! What do, what do you want to do?
Sheldon: I don't know. What do you want to do?
Penny: I don't know. What do you want to do?
Leonard: I'm starting to remember the problem with Anything Can Happen Thursdays.

• Permalink: I'm starting to remember the problem with Anything Can Happen Thursdays.
• Added: April 24, 2014

Amy: Maybe you could make your new field of study the calculation
of nuclear matrix elements.
Sheldon: Oh, please. If I wanted to take up a fad, I'd get a tramp stamp.

• Permalink: Oh, please. If I wanted to take up a fad, I'd get a tramp stamp.
• Added: April 11, 2014

Clogzilla. That's pretty funny. I don't think that's gonna pass.

• Permalink: Clogzilla. That's pretty funny. I don't think that's gonna pass.
• Added: April 11, 2014

Penny: Wait. What's wrong with geology?
Sheldon: Let me put this in a way you'll understand, Penny. You remember how you explained to me that the Kardashians aren't real celebrities? Well, geology is the Kardashians of science.

• Permalink: Let me put this in a way you'll understand, Penny. You remember how you explained to me that...
• Added: April 11, 2014

Penny: I gave him a new look. It's cute, huh?
Amy: Yeah, it's cute. That's the problem. I don't need other girls to see him walking around like sex on a stick.
Sheldon: She's right. I'm too hot.

• Permalink: She's right. I'm too hot.
• Added: April 11, 2014

Sheldon: Am I wasting my life on a theory that can never be proven?
Howard: Maybe. But how great is Game of Thrones?

• Permalink: Maybe. But how great is Game of Thrones?
• Added: April 11, 2014

Amy: Y-You'll feel better after you eat.
Sheldon: Okay.
Amy: What-what do you want, like, Thai food? A... a burger?
Sheldon: I don't know!

• Permalink: You'll feel better after you eat
• Added: April 04, 2014

Sheldon: Quick poll: PS4 or Xbox One? Raj.
Raj: Uh, Xbox One.
Sheldon: Penny.
Penny: Huh?
Sheldon: Leonard.
Leonard: PS4.
Sheldon: Wolowitz.
Howard: Both great.
Sheldon: Bernadette.
Bernadette: I like the Wii.
Sheldon: Thanks, Grandma

• Permalink: Thanks, Grandma
• Added: April 04, 2014

Penny: Next time I get pulled over for a speeding ticket, here come the waterworks.
Sheldon [running to bathroom]: Here come the waterworks!
Leonard: Aren't you gonna ask?
Penny: What is this, my first day?

• Permalink: What is this, my first day?
• Added: April 04, 2014

Sheldon: Boy, do I have to urinate.
Leonard: If only there were a solution
to that.
Sheldon: Seriously. I feel like I've got
a fish tank in my pelvis.

• Permalink: Seriously. I feel like I've got a fish tank in my pelvis.
• Added: April 04, 2014

Sheldon: ... now you're going to need a stronger friend named latex.
Mrs. Cooper: Are you having the sex talk with me?
Sheldon: Well someone has to.
Mrs. Cooper: Oh, dear Lord!
Sheldon: Yeah, well... No, don't look at him, he's mad at you right now.

• Permalink: Yeah, well... No, don't look at him, he's mad at you right now.
• Added: March 13, 2014

Sheldon: Then why are you doing it?
Mrs. Cooper: Because I'm not perfect, Shelly. And that man's booty is.

• Permalink: Because I'm not perfect, Shelly. And that man's booty is.
• Added: March 13, 2014