Skye: Usually one person doesn't solve the solution, but 100 people with 1% of the solution that will get it done. I think thats beautiful, pieces solving a puzzle.
Ward: You and I see the world differently.

Melinda: You can't save someone from themselves, sir.
Coulson: You can if you get to them early enough [looks at Skye].

You should know, I'm not a fan of being poked.

Coulson

Ward: And the attackers?
Coulson: Invisible.
Skye: Wait Invisible? So cool, but terrible.

Coulson: Sounds like there's a lot you're willing to forgive.
Daisy: I will never forgive him. He murdered Rosalind just to hurt you. He killed Koenig because of me.
Coulson: He knew once Koenig outed him as HYDRA he'd lose you.
Daisy: And the sad part is, that's when I finally understood him for the first time. The reason Ward kills isn't because he feels nothing. It's because he feels too much.

You and Simmons are so tight, it's like you're psychically linked.

Skye

I don't want you to die, I want you to suffer.

Daisy

I wanted it to be a person. Some super powered psychopath. Someone I could hurt. Someone I could punish. That I could do. What I can't do is protect you guys from stuff I can't even see or understand.

Ward

LMD May: Today wasn't great.
Coulson: Cauliflower isn't great. Today was a kick in the balls.

Ward: She's a groupy, all the hacking into SHIELD, tracking powers. She might as well be one of those sweaty Cosplay characters crowding around Stark tower.
Skye: WHAT?! I would... [whispers] it was just one time.

Hill: Then New York was invaded by aliens, and they were beaten back by among others, a giant green monster, a costumed hero from the 40s, and a god.
Ward: I don't think Thor is technically a god
Hill: You haven't been near his arms.

As far as I'm concerned, you're just another redshirt, like so many others who tried to stop me from saving the world. So, cool original story, bro. But this means nothing to me.

Coulson [to Ivanov]

Agents of S.H.I.E.L.D. Quotes

Kasius: Yo-Yo Rodriguez? How peculiar.
Yo-Yo: Says the space mime!

Sousa: Hey, what are you doing up?
Daisy: Why do you care?
Sousa: Because you don't.