Izzie: YAY! Oh, that's the one!
Bailey: Very dapper Dr. Shepherd.
Derek: You're serious about this? It's not some cruel joke?
Izzie: You look fantastic. He looks fantastic right?
Meredith: Yeah.
Cristina: Whatever.
Alex: Yeah.
George. Yeah.

Alex: Chicken.
George: Good chicken.
Meredith, Cristina: It's chicken.
Izzie: I know it's chicken! I wanna know what it tastes like.
Alex: Tastes like chicken.
Izzie: I'm having surgery today.
Bailey: Maybe, if the meds are strong.
Izzie: I am maybe having surgery today, and as such I cannot taste the chicken for myself. So I really need you guys to tell me what it tastes like. I need to nail down this dinner, so I can announce it on Meredith and Derek's wedding website.
Meredith: There's a website?
Izzie: So, can you please be a little more articulate than just chicken?

[narrating] Remember when we were little, and we would accidentally bite a kid on the playground? Our teachers would go "Say you're sorry." And we would say it, but we wouldn't mean it. Because the stupid kid we bit, totally deserved it. But, as we get older, making amends isn't so simple. After the playground days are over, you can't just say it. You have to mean it. Of course, when you become a doctor, sorry is not a happy word. It either means you're dieing and I can't help. Or, it means this is really gonna hurt.

Meredith

[narrating] To do our jobs we have to believe defeat is not an option. That no matter how sick our patients get, there's hope for them. But, even when our hopes give way to reality and we finally have to surrender to the truth, it just means we've lost today battle. Not tomorrows war. Here's the thing about surrender, once you do it, actually give in, you forget why you were eve fighting in the first place.

Meredith

Meredith: So I guess a big wedding won't be that bad.
Lexie: I'm just sad 'cause I didn't get a chance to see you in the actual dress.
Meredith: You will.
Lexie: How? I mean, if Derek and Mark don't make up how...
Meredith: You're my sister Lexie. You're in the wedding.
Lexie: Oh my god. I'm gonna be a brides maid? Oh my god, I don't know what to say.
Meredith: Well, you should wait and see what Izzie's picked out for you to wear. Then you'll have plenty to say.
(Mark and Der walk in... together)
Derek: Do you want one?
Mark: So much. We can still catch the last half of the game.
Derek: Yeah, that's what I was thinking.
(Mer and Lexie look on dumbfounded)
Meredith: You can stop eating now.
Lexie: Oh thank god!

(to Meredith) You make a beautiful bride.

Izzie

Bailey: Is there anything else you need before I go?
Arizona: No. You wanna sit a while?
Bailey: No, I do not want to sit. I've been sitting and lying down all day.
Arizona: Dr. Bailey.
Bailey: Holding a child. If I wanted to spend the day holding a child, I would have stayed home to hold my own child. I didn't do a single medical thing today. I didn't even put a band aid on a patient. I'm... I'm just tired. I'm done.
Arizona: Are you gonna tell your husband?
Bailey: What would I tell him?
Arizona: That it's more than just cutting. Pedes is more than just cutting. And, what you did today was heroic, and you know it.
Bailey: Ok. Maybe I'll tell him that.

Mark: You know that's the first actual compliment you've ever given me?
Derek: It wasn't a compliment, it was a simple statement of fact.
Mark: See, why do you do that? Why can't you just give a person a compliment?
Derek: If you have to ask for a compliment, it's not a compliment. Are you asking for a compliment?
Mark: Yes!
Derek: Then it's not a compliment!

Derek: He has a long recovery ahead of him. He has severely damaged his facial nerves, shattered his inner ear, and lost a great deal of blood.
Patient's wife: Oh my god.
Mark: But, he'll be fine. He'll be in some pain for a while, but he'll be fine.
Patient's wife: Oh my god, thank you. Thank you both so much.
Derek: Thank Dr. Sloan. That kind of bleed, not many surgeons could have handled. He saved your husbands life. Would you like to see your husband now?
Patient's wife: Yes, thank you.

Owen: I jumped. In front of her car. And she was just driving to the bank.
Dr. Wyatt: Are you talking about Cristina?
Owen: I jumped in front of her. I knew, I knew I wasn't together. I knew no good for her, or for anyone. And I wrecked her. And that is unforgivable. I don't forgive myself for that. I can't forgive myself for that. And I feel shameful about that. That is what I fell today. Shame.
Dr. Wyatt: Good. That's a start.
Owen: How is that a start?
Dr. Wyatt: You named it. The feeling. You have to know what it is, before you can start to navigate to somewhere better.

Arizona: What happened?
Callie: He ah, gave me an ultimatum. He said if I didn't come home, he'd take away my trust fund. He'd cut me off. So, I cut him off. I mean, if he can't accept me for who I am... I cut him off.
Arizona: Are you ok?
Callie: No. I mean yeah, I... don't know.
(Callie starts to cry. Arizona hugs her)
Arizona: Oh.

Cristina: 98 over 72. That's good. That's good.
Izzie: Don't. Don't try to make me up better than I am because I'm not. I'm sick.
Cristina: You had an incredibly high dose of IL2 today, this is how you're supposed to feel.
Izzie: All I wanted to do today was flip through magazines, and call caterers, and make Mer try on dresses I knew she'd hate. I thought it would be fun or funny. I thought I could be the same person I was when I woke up this morning, but I'm not. I'm just another patient trapped inside a sick, dieing, cancer ridden body.

Grey's Anatomy Season 5 Quotes

[walking by Izzie's room]
Meredith: Hot.
Sadie: Horny.

Arizona: Maybe we're bouncier in ped's, than in general surgery. But I thought there would be a yay! Or some jumping around. 'Cause you look pretty dower for someone whose about to start a highly prized fellowship. You are about to start a highly prized fellowship right?
Callie: Hey, I've got a plan to stop George, you in?
Arizona: Stop George from what?
Bailey: Ah, he joined the army. Yes. I'm in.
Arizona: Bailey, I'm talking to you! Why are you trying to stop him?
Callie: Because he joined the army.
Arizona: And?
Callie: And, because he's my ex husband, and I know his mom and I love his mom. And, normally Izzie would talk sense into him but, she's got cancer, and kind of a bad mental deficit. So, it's on me to stop him.
Arizona: Why would you wanna stop him?
Callie: Because he joined the army. Don't you think that's a problem?
Arizona: I think that's awesome.
Callie: Awesome?