Sometimes your lack of social skills astonishes me.

Sheldon

It was a lot of work to accommodate you in my life. I'd hate to think that effort to be in vain.

Sheldon

Sheldon: This is for you
Penny: Ice cream?
Sheldon: I've been familiarizing myself with female emotional crises by studying the comic strip, "Cathy." when she's upset she says, "ack" and eats ice cream.
Penny: Ack.
Sheldon: If you were a cat, I would have brought you lasagna.

Raj: Ahh, the premature I love you.
Wolowitz: : I guessed premature, does that count?

Sheldon: Enjoy the accolades now, Wil Wheaton. But like your time on Star Trek: The Next Generation, your smug self-satisfaction will be short-lived.

A common spare. The Miss Congeniality of the Bowling Pageant.

Sheldon

What did you do, Romeo? Did you pour maple syrup all over your body and ask her if she was in the mood for a short stack?

Wolowitz

Wolowitz: Why is Leonard being a giant douche? That is, assuming, of course that giant douches are possible.
Sheldon: Of course they are -- Leonard's being one.

Wolowitz: Okay forgot giant ants. How about giant rabbits?
Raj: Big or small, I don't like rabbits. They always look like they're about to say something, but they never do.
Sheldon: Rabbits do have a respiratory system that would support great size. And as a side note, they are one of the few animals whose scrotum is on the front of the penis.
Raj: Maybe that's what they want to talk about.

Leonard: If my PE teachers told me this is what I was training for I would have tried a lot harder.
Penny: Do or do not, there is no try.
Leonard: Did you just quote Star Wars?
Penny: I believe I quoted Empire Strikes Back.
Leonard: Oh my God. I'm lying in bed with a beautiful woman who can quote Yoda.

Didn't work. This alcohol is defective.

Sheldon

A neutron walks into a bar and asks, "How much for a drink?" The bartender says, "For you? No charge."

Sheldon

The Big Bang Theory Season 3 Quotes

Wolowitz: Sheldon. You remember the first few weeks; we were looking for magnetic monopoles and not finding anything, and you were acting like an obnoxious, giant dictator?
Raj: I thought we were going to be gentle with him.
Wolowitz: That's why I added the "tator"

Wolowitz [after seeing Penny jump Leonard]: Damnit, I should have gone over and said we were back
Raj: Yeah, it was "first come, first serve."