No wonder you got cancer, Cathy. You're so full of lies and evil, you gave it to yourself.

Sean

From now on, I am fighting for my life, not yours. You, my brother, can suck it and fuck it.

Cathy

With all the educated cock I've had it my mouth, it's cruel irony that my baby daddy is a bipolar dropout.

Rebecca

I can't see you as a patient, Cathy. Because I don't see you as a patient.

Todd

Andrea: They take all the mirrors out of your house or something? You don't look good.
Cathy: Thank you! Finally someone telling me the truth.

You be wowed. I'll be drunk.

Cathy

Paul: Can we at least figure out what to tell Adam? Because right now, my story is: "Adam, your mom's a meanie!"

We have to do this before I get fat and you get all... cancer-y.

Rebecca

I don't wanna feel better. I wanna be better.

Cathy

Cathy: You think you're having fun right now?
Sean: Well, the tent's pretty cool.

I can't bring myself to intentionally puncture myself. I'd make a crappy heroin addict.

Cathy

Andrea: Don't freak out.
Cathy: Telling people not to freak out is not a great way to set people at ease.

The Big C Quotes

Sean: The last you could do is buy a damn Hybrid.
Cathy: The least you could do is take a shower.

Paul: Can we at least figure out what to tell Adam? Because right now, my story is: "Adam, your mom's a meanie!"