Colonel Burns, why ... I haven't heard my father's name in years.

Mr. Burns

Ned: Homer, God didn't set your house on fire.
Reverend Lovejoy: No, but He was working in the hearts of your friends and
neighbors when they came to your aid, be they Christian (Ned), Jew (Krusty), or ... miscellaneous (Apu).
Apu: Hindu! There are 700 million of us.
Reverend Lovejoy: Aw, that's super.

Insurance Guy: Any valuables in the house?
Homer: Well, the Picasso, my collection of classic cars--
Insurance Guy: Sorry, this policy only covers actual losses, not made-up stuff.
Homer: Well that's just great!

Barney: What are these axes for?
Chief Wiggum: I dunno, chopping stuff.
Barney: Gotcha. (chops down the Simpson's mailbox)
Chief Wiggum: That's some nice choppin'.

After that fateful day I could never even look at Eliza again. It didn't help that the next day he drank bad well water and went blind.

Milhouse [reading diary]

Homer: Oh, the song. The song. (sings) When the fire starts to burn, there's a lesson you must learn. Something something, then you'll see: You'll avoid catastrophe! D'oh!

A little schmutz, a little schmear, and presto, you're part of the underclown railroad.

Krusty

A week ago, I had no idea of what the future would bring, which I guess is true of everyone all the time

Lisa [reading Eliza's diary]

Marge: I'm going to ask you one last time. Are you sure you won't come with us to church?
TV Announcer: Coming up next: make your own ladder!
Homer: Very sure.

Yeah, the Simpson family is a long line of horse thieves, deadbeats, horse beats, dead thieves and a few alcoholics.

Homer

Willie: I'll have to use explosives.
Bart: Explosives? Great! [takes out map] If we put charges on the load bearing walls, we can blow up detention hall, leaving art class okay.
Willie: Hmm?
Bart: What! I like art, okay?
Willie: I'm blowing up the stump, not the school.
Bart: Right right, you never saw that.

Bart: Unckie Herb, what advice would you give to a young boy who would most likely become a bum like yourself?
Herb: Discarded pizza boxes are an inexpensive source of cheese.

The Simpsons Quotes

Larry: What you got riding on this?
Homer: My daughter.
Larry: What a gambler!

Maggie? Oh, you must be sick. Let's see, what's old Dr. Washburn prescibe? Do you have dropsy? The grippe? Scofula? The vapors? Jungle rot? Dandy fever? Poor man's gout? Housemaid's knee? Climatic poopow? The staggers? Dum-dum fever?

</i> Abe