And Then There Were Fewer
Family Guy Season 9 Episode 1 (09/26/10)
During the Family Guy season nine premiere, James Woods invites all his enemies to his house and we're treated to a Clue-style mystery. Spoiler alert: everyone thinks Tom Tucker did it, but it turns out to be Diane Simmons. Lois finds out in the end and Stewie saves her life in the nick of time.