It's Blair's 20th birthday party and I'm still acting like an eighth grader.

Dan: So I wrecked Blair's birthday and I betrayed Nate, I disappointed my dad. And as the icing on the cake I pretty much ruined his and Lily's anniversary.
Vanessa: Other than that, how was your night?

Dan: Chuck. Hey man, I was just stopping by to see Nate but I guess he's not here.
Chuck: He's in his room.
Dan: Oh he is? He's... not in class? I would have thought—
Chuck: You don't really know how to stage a run-in, do you?

Dan: So much for Zen Jenny Humphrey.
Jenny: Come on, Dan. I just what needed to be done.
Dan: It's what Blair and Chuck would have done.

Chuck: Before you say anything I'm only calling because I saw Gossip Girl. I wondered if I might be able to offer some assistance.
Dan: Well unless it's a murder-suicide I think I'll pass.
Chuck: So dramatic. You should be a writer.

Chuck: I heard Jenny was back. I wanted to speak with her.
Dan: And say what? "I'm sorry for taking advantage of you and letting my psycho ex-girlfriend run you out of town"?
Chuck: Something like that. Except without the sarcasm.

I don't know if I can have this same conversation one more time.

Nate: Thanks for coming with me man.
Dan: No problem. I shouldn't have told you about the cotton swab thing. That was insensitive.

Dan: You guys haven't ...
Nate: No. I spent the night at her place, but I took a page from the ol' Humphrey playbook and we just talked and played Scrabble.

Nate: Juliet and I have this nice little evening planned after the mixer. Got some nice champagne, new Matteo sheets ... and I'm hoping some recently purchased lingerie.
Dan: That's for her, right?

Not only am I manly and rugged, but I also have mad browsing skills.

[to Vanessa] I'm sorry, mom, I didn't realize when we moved in you'd be laundry monitor.

Gossip Girl Quotes

Even Blair Waldorf can not bend DNA to her will.

Dan

Hazel: Do you know what you're doing, Little J?
Jenny: I'm not Little J anymore.