Peter: I put our family on the map tonight. No longer will we be just those faceless nobodys who brought the bird flu to Quahog.
Lois: You know, there's something seriously wrong with the man who always puts his friends over his family.
Brian: Come on, Lois, I think you're overreacting. What's so wrong about a guy hanging out with his buddies?
Lois: Buddies? You're one of his buddies?
Brian: Yeah, and you know why? 'Cause I don't try to tell what he can and can't do.
Lois: Oh, please, Brian. You're just two people living in the same house. If you didn't, you'd never hang out with each other in a million years. He owns you. You're his property.

Lois: Wow, congratulations on your grand re-opening, Mort! Looks like your customers are coming back!
Mort: Thanks, Lois! It's good to be up and gouging again!

Lois: Peter, will you stop being so jealous? I dated Ross 20 years ago.
Peter: That's right, that means he had you first, Lois. I'll always be Scottie Pippen to his Michael Jordan.

Hey, it's cooked food in another house. That's exciting for light older women like me.

Peter: Guys, be sure to look down the whole time. It's really deep and freaky and disoritenting! [falls] It's okay, there'a huge pile of dead bodies down here that cushioned my fall.
Lois: Do any of them seem like they have any extra tampons in their backpack?
Peter Uh, no.
Lois: No like you checked and there aren't any no, or no you're just assuming?
Peter: I'm embarassed.

Lois: Peter, you left the flap open!
Peter: It's like a thousand degrees in here, Lois!
Lois: Close the tent now, it's freezing!
Peter: Headline: "Woman Cold."

Lois: We made it! We proved that we're not second best!
Ross Fishman: Well, look who finally got here!
Lois: You beat us?
Pam Fishman: Don't feel too bad. We only beat you by one hour, twelve minutes, and forty-two seconds.
Ross: And quite frankly, we're bored of it up here. So you guys enjoy it, we're gonna head back down.

Lois: You guys shouldn't have done this!
Stewie: Hey, any time you can celebrate the end of someone's periods.

That sounds awfully lonely, like being an NBA player on the road.

Brian: I think, I think we're launching!
Lois: Oh my god, everyone strap yourselves in! Stewie, hold my hand.
Stewie: No thanks, I prefer to die giving you the finger.
Peter: If this is what it takes to get out of Florida, fine.

Lois: Remember kids, if it's terrible, at the end we all say "You did it!"
Stewie: I can't believe we're going to the theater the same day Chris drowned a mouse in a puddle. I mean, don't we need a day to clear our heads?

Lois: It's like our privates were shaking hands after a successful business deal in a swamp!
Peter: To me, it just proves that we're truly meant to be together.
Lois: I love you, Peter.
Peter: I love you too, Lois. [beat] By the way, you may have to become a full-on prostitute because our phone bill was $7,000.

Family Guy Quotes

Aunt Margarite [on her video will]: Lois, you were always my favorite niece; I just knew you would find a wonderful man who would make all your dreams come true. But I was wrong.
Peter: And now you're dead. Score one for Peter

But now that you mention it, your face looks like a used condom.

Quagmire