Oh god how do you get pink-eye? This is got to be it!

Peter: I missed you Brian.
Brian: I missed you too Peter.
Peter: And now Im gonna go upstairs and pee in Meg's bed.
Brian: No, we're going to go pee in Meg's bed.
Peter: Good boy.

Brian: Well I don't know if I'd label myself a drinker. I know I like a cold beer after I mow the lawn.
Peter: There were three lies in that sentence.

We act like we didn't take a lot from The Simpsons, but we took a lot from The Simpsons.

Hey, Meg, I like your new boyfriend. Every pot finds a lid, huh?

I'm as creative as the first spider to spin a web.

What if God is a serial killer? He lowers the average lifespan of humans to 65.

I can't go to jail. They'll razz me good on account of my belly.

Meg: Trust me, I know more about getting bullied than anyone.
Peter: You do? How?

The only way to settle a family dispute is in the cage.

There are gaps in my knowledge. This is hardly news.

Or you can pull the hose out of the bucket and let the hose run free.

Family Guy Quotes

Aunt Margarite [on her video will]: Lois, you were always my favorite niece; I just knew you would find a wonderful man who would make all your dreams come true. But I was wrong.
Peter: And now you're dead. Score one for Peter

But now that you mention it, your face looks like a used condom.

Quagmire