Peter, Peter! There's so much doodie in here.. I can't take it anymore.... I haven't eaten in four days cause... I just can't fit anymore in there. Help me.

You know, mother, as first lady of the American stage Helen Hayes once said, "I'm going to kill you"

Olivia: You are the weakest link, goodbye.
Stewie: Ha ha ha! Oh gosh that's funny! That's really funny! Do you write your own material? Do you? Because that is so fresh. You are the weakest link goodbye. You know, I've, I've never heard anyone make that joke before. Hmm. You're the first. I've never heard anyone reference, reference that outside the program before. Because that's what she says on the show right? Isn't it? You are the weakest link goodbye. And, and yet you've taken that and used it out of context to insult me in this everyday situation. God what a clever, smart girl you must be, to come up with a joke like that all by yourself. That's so fresh too. Any, any Titanic jokes you want to throw at me too as long as we're hitting these phenomena at the height of their popularity. God you're so funny!

You know mother, life is like a box of chocolates. You never know what you're going to get. Your life, however, is more like a box of active grenades!

Stewie: Are you blood brothers with Meg because you ate her tampon out of the trash?
Brian: No, that, that's something else.

Peter: Hey, Stewie, nice sunburn! (Slaps him on the back)
Stewie: Aaah, you horse's ass!

Asian Santa: (really fast) What you want? What you want for Christmas?
Stewie: Um, I was thinking maybe one of those old timey...
Asian Santa: (really fast) Too late! Take too long! Sad Christmas!
(throws Stewie and an Asian kid comes) What you want?
Asian Kid: (really fast) Fire truck!
Asian Santa: What color?
Asian Kid: Red!
Asian Santa: Next. (throws kid)

(Stewie is standing in the mirror, peeling off his dead skin)
Brian: Ewww!
Stewie: Hey Brian, you want some Stewie jerky?

(Brian and Lois are downstairs awaiting Meg to come down so Brian and Meg can go to the dance)(Stewie and Meg walk down the stairs)Stewie: Here she is, Brian I present to you your polish turd for the evening.Meg: How do I look Brian?Brian: Ahhhhhh.....you sure do Meg.

Lois: What's going on down here?
Stewie: Uhh... we're playing House.
Lois: That boy's all tied up.
Stewie: Roman Polanski's House

Sgt Angryman: Where are you from boy?
Stewie: Quahog
Sgt. Angryman: There are only two things in Quahog steers and queers and I don't see any antlers. So what does that make you?
Stewie: Queer?
Sgt. Angryman: Right!
Stewie: Oh did I get it?

Stewie: Brian, did you see Revenge of the Sith?
Brian: Yeah, I saw part of it.
Stewie: Why does Emperor Palpatine have a desk?
Brian: Huh?
Stewie: In that scene where Yoda comes in and they're about to have that big fight, Emperor Palpatine clearly gets up from his desk. I'm just saying, what does he...what does he need a desk for?
Brian: Who the hell cares?
Stewie: I'm just saying, it's weird. I mean, like, what was he doing at his desk right before Yoda walked in? What was he doing? Was he doing paperwork? Was he, like, "Uh Yoda, what do you need, and will it take longer than five minutes? I'm absolutely swamped. These requisition forms for new TIE fighters have to be down to Debbie in accounting by six or Nute Gunray is gonna pitch a tent in my waiting room."

Family Guy Quotes

Aunt Margarite [on her video will]: Lois, you were always my favorite niece; I just knew you would find a wonderful man who would make all your dreams come true. But I was wrong.
Peter: And now you're dead. Score one for Peter

But now that you mention it, your face looks like a used condom.

Quagmire