One person in your life, one sentence, has the power to change you forever.

Radcliffe [to Daisy]

I know no one wants to hear they're just an avatar in a digital prison, but sometimes that happens and here we are.

Simmons [to Mace]

Ivanov: I didn't know a machine could be on edge.
Aida: It is not. I am simply recalibrating after a setback within the Framework.

If history's taught me anything, it's that good intentions don't come to anything unless there's a steady hand to guide them.

Coulson

I don't want the public placated. I want them afraid.

Fitz

I could have changed my life that day, but it seemed like too much responsibility. I didn't want to shoulder it.

Coulson

Hey, I'm not going to pretend to get all of this, but I'm here to help.

Trip [to Simmons]

If more people see what you saw, maybe they'll fight back too.

Daisy [to May]

Mack, I get it. These wounds don't heal overnight. But for reasons I can't explain, I trust this woman. Maybe you should too.

Coulson [to Mack, on May]

You're right. I can't show any weakness. Which means I can't tolerate failure. Even from my own father.

Fitz

My days of following blindly are over. If there's any truth to what you're saying, you'll have to show, not tell.

May [to Coulson]

What if I told you this whole world wasn't real?

Coulson [to May]

Agents of S.H.I.E.L.D. Quotes

Kasius: Yo-Yo Rodriguez? How peculiar.
Yo-Yo: Says the space mime!

Sousa: Hey, what are you doing up?
Daisy: Why do you care?
Sousa: Because you don't.