Quagmire: What was Simon without Garfunkel?
Peter: Wildly successful?

Whose leg do you gotta gagoosh to get an Amaretto around here?

Vinny

Peter: Peter: My hog cannot partake in the slop this evening.

This shouldn't embarrass you, the size should embarrass you.

Lois [to Peter]

You know you've made it when you've got a teenage boss.

Stewie

Says 'Glenn Quagmire.' But if you squint and imagine it says 'Peter Griffin,' it says 'Peter Griffin'!

Peter

Stewie: Are you blood brothers with Meg because you ate her tampon out of the trash?
Brian: No, that, that's something else.

Oh my god, look at you! You're more herpes than dog!

Stewie

Oh my god! Your mouth looks like the underside of a boat!

Teacher

We're supposed to stick together! Like goatee guys at a barbecue!

Peter

Scumbag: Smells like this guy's already wet himself.
Peter: Don't flatter yourself--that was from this morning.

You've got herpes, too? This house is like backstage at a Whitesnake concert.

Stewie

Family Guy Quotes

Aunt Margarite [on her video will]: Lois, you were always my favorite niece; I just knew you would find a wonderful man who would make all your dreams come true. But I was wrong.
Peter: And now you're dead. Score one for Peter

But now that you mention it, your face looks like a used condom.

Quagmire