Brian: Oh my god, Stewie, it worked! We're in Vegas!
Stewie: Yeah, alright! Let's go to the hospital, get checked for teleportation cancer, and then party!

Thank God we're finally here. Kind of weird that they showed Flight 93 on Flight 93.

Brian: Peter, this is the final plague!
Peter: Good cause this is starting to get old

Brian: It's amazing, Peter. You've inspired the whole neighborhood to work together.
Peter: You know what's really amazing? I haven't brushed my teeth in three days, and no-one has said a thing

Dr. Kaplan: I'd like to pat you Brian. Would that be okay? You're a good dog, Brian. A very good dog.
Brian: Keep it above the waist, Doc

Hey, its Thanksgiving. Shouldn't you be in Detroit losing a football game right about now.

Joe: Sex is overrated.
Peter: Stay out of this Joe.

Peter: Is that the one where they make his dress in little shorts and hats like the guy from AC/DC?
Brian: Yeah. Why does he wear that outfit?
Peter: 'Cuz he rocks!

Stewie Also, I gave the string quartet the music for highway to the danger zone
Brian: You have the sheet music for highway to the danger zone?
Stewie: Uh, yeah, that's all I keep in here. It's power bars and sheet music

Brian: Excuse me Mr. Hemingway. Can I have a beer with you?
Ernest Hemingway: Sure, I love life and all the people in it.
Brian: Thanks and, as a fellow writer, I'd love to talk to you about your craft God if only we can get rid of these damn arms and attach the pen directly to the heart.....
[Hemingway shoots himself]

Brian: What's on his arms?
Stewie: Those are waterwings. He was terrified of the water.

Brian: Okay, just to be clear, we were talking about me being in love with you and you rejecting me, right?
Lois: Yes.
Brian: I'm just making sure.... Say we were both drunk and we knew we wouldn't remember...
Lois: Well, I'd have to be really, really... No!

Family Guy Quotes

Aunt Margarite [on her video will]: Lois, you were always my favorite niece; I just knew you would find a wonderful man who would make all your dreams come true. But I was wrong.
Peter: And now you're dead. Score one for Peter

But now that you mention it, your face looks like a used condom.

Quagmire