Brian: Peter, did you read the fine print on this loan contract?
Peter: Um, if by "read" you mean imagined a naked lady, then, yes

Jasper: You like sex in the city?
Brian: I don't watch that show.
Jasper: I wasn't talking about the show. Ooh, I'm nasty! (Imitates foghorn) Someone put me out to sea!

Hey, how about a little less questions and a little more shut the hell up

Meg: Wow, Brian! Have you lost weight? You gotta tell me your secret!
Brian: Here's a hint: Put down the fork!

Brian: What are you doing here [at rehab]?
Peter: I'm on vacation. Oh, and if anyone asks, I'm also on smack

Brian: The real hero here is God: for blessing me with this nose, and a few other amazing appendages!

Brian: So I see you got a new receptionist. Nice little body on her, huh?
Therapist: That's my daughter.
Brian: Well, we could probably call this an early day, huh?

Brian: I think, I think we're launching!
Lois: Oh my god, everyone strap yourselves in! Stewie, hold my hand.
Stewie: No thanks, I prefer to die giving you the finger.
Peter: If this is what it takes to get out of Florida, fine.

Brian: Ah, the old alma mater. I tell you, there's something magical about Brown.
Chris: Brown is the color of poo. Ha ha ha!
Brian: Yes. Yes it is

Brian: Wow, this is amazing, every major playwright is here.
Stewie: Yes, and it seems to be quite the successful party. Several of them have already committed suicide.

Brian: I just wish I could have had five years to be good.
Stewie: There's your voice, Brian. It's a depressing voice, but it's yours. Write from that.

Brian: Face it, Peter. It's over. Why don't you sit down with the mayor and negotiate some kind of treaty?
Peter: Negotiate? Peter Griffin doesn't know the meaning of the word "negotiate."

Family Guy Quotes

Aunt Margarite [on her video will]: Lois, you were always my favorite niece; I just knew you would find a wonderful man who would make all your dreams come true. But I was wrong.
Peter: And now you're dead. Score one for Peter

But now that you mention it, your face looks like a used condom.

Quagmire