I'm Dr. House. How long have you been a psychopath?

House: You're invoking the guy code?
Wilson: We're guys. It's a code.

Ramon: Faith is not a disease.
House: No, of course not. On the other hand, it is communicable, and it kills a lot of people.

Anybody can hate humanity after getting shot. Takes a big man to hate it beforehand.

Did Cameron get you hair in the divorce?

House [to Chase]

We're two tigers away from an act in Vegas.

You were thinking about Wilson while we were having sex? That's so cool! So was I.

House: I've been busy.
Cuddy: Doing what?
House: You.

House: Just because my sausage has been filling your bun doesn't mean you get to decide what flavor chips I nosh on during the day.
Dr. Cuddy: Nope, I get to do that because I'm your boss.

House: Black guy campaigning for the opposition? Does Obama know about this?
Dr. Foreman: I tried calling him on the brother hotline. He didn't pick up.

House: Nothing will ever be simple again.
Masters: That's fine with me.

Dr. Foreman: Notice anything odd about the shape of the fluid collection?
House: Oh, God, it's... the Virgin Mary.

House Quotes

Dr. Cameron: House doesn't believe in pretense. Figures life's too short and too painful. So he just says that he thinks.
Dr. Foreman: "I say what I think" is just another way of saying "I'm an assho"...

(about House) The son of a bitch is the best doctor we have.

Dr. Cuddy