Brian: Lois, I really like to talk about this.(Brian starts scratching the door)
Lois: No! Stop scratching the door!
Brian: Okay.

Lois: (after reading Peter's note) Well, heh, it looks like I am free. Hey, you know what might be fun? How bout we just order room service and watch a couple of bad movies?
Brian: Yeah, that does sound like fun. I'll go rent Vanilla Sky.
Lois: I said a bad movie, not an abortion.

Lois: I don't know, Brian. Raising a child is a very rewarding experience.
Peter: You know what else is rewarding, Lois? Shutting your Vag.
Lois: What?
Peter: What?

Peter: Here's the deal: anything he lops off we get to bring home to Brian.
Lois: That's very green of you, Peter.

Han/Peter: Well your manage-to-keep-me-around-a-little-longer ness, it looks like you've managed to keep me around a little longer.
Leia/Lois: I assure you, I had nothing to do with it.
Han/Peter: Yeah right. I think you just can't stand to let a fat guy like me out of your sights.
Leia/Lois: [agitated] Why you stuck up, half witted, scruffy lookin' nerf herder!
Han/Peter: You can't use that word! Only we can use that word!

Leia/Lois: We're gonna be pulverized!
Han/Peter: Look, we got four or five of the main characters on board this ship, so I think we're okay.

Princess Leia/Lois: There's something out there!
Han Solo/Peter: Where?
Princess Leia/Lois: Out there in the cave!
Han Solo/Peter: Ha! Crazy women always hearing thngs.
Chewbacca/Brian: There's something out there!
Han Solo/Peter: Let's go check it out.

No, you're a lady bigshot... like Miss Piggy!

I think there was actually more wind back then.

No, no, Peter, you're still you; you're just a teenager, you're not switching genders.

Lois: Chris, have you been drinking?
Chris: Yes, have you been aging?

Lois: Is it a blood diamond?
Peter: Only the bloodiest.

Family Guy Quotes

Aunt Margarite [on her video will]: Lois, you were always my favorite niece; I just knew you would find a wonderful man who would make all your dreams come true. But I was wrong.
Peter: And now you're dead. Score one for Peter

But now that you mention it, your face looks like a used condom.

Quagmire