Donna: Oh Lois, I'm so glad to see Peter and Cleveland back together again.
Lois: Yeah, me too. Now Peter will have something to do besides flushing the toilet to Foghat's "Slow Ride."

Lois: Oh, look who's back; the grave robber.
Peter: Hey, Lois.
Lois: So, what happened? You find your treasure?
Peter: No, I realised something after you left; It's not the treasure that matters. All that really matters is the money you get in exchange for the treasure. I guess I had to learn that the hard way.

This shouldn't embarrass you, the size should embarrass you.

Lois: Doctor, do you think the brain tumor could have anything to do with Brian's recent behavior?
Doctor: Hmm, I haven't heard of brains being linked to behavior, but I suppose anything's possible.

Chris: Mom, is dad gonna die?
Lois: Well Brian's the one with the brain tumor.

Lois: Is that what you really thoguht?
Peter: I did, I really did.

You shouldn't have to do porn to feel appreciated.

Lois: I thought you said you'd take care of it!
Peter: I did. He slept with it, now he'll slowly grow to hate it for the next 20 years.

Chris: Hey Heather I made your favorite cookies, now I want to hear about your day.
Peter: Hey Lois I heard Katherine Heigl likes to french kiss.
Lois: Oh my god, Chris treats that pile of junk better than Peter treats me!

Chris: It's made of skittles! You want to eat the baby together on the way home?
Lois: Yeah, I'd like that.

Lois: Oh I'm not doing anything special, just sitting here with the baby.
Stewie: Screw you too.

Peter: Alright, lets dope her up good -- get that mouth off her.
Cleveland: No Peter! The problem is you!

Family Guy Quotes

Aunt Margarite [on her video will]: Lois, you were always my favorite niece; I just knew you would find a wonderful man who would make all your dreams come true. But I was wrong.
Peter: And now you're dead. Score one for Peter

But now that you mention it, your face looks like a used condom.

Quagmire