Meg: Mom, I can't clean, I've got stuff to do.
Lois: Meg, we all know you don't have stuff to do

Chris: My dad is smarter than your dad.
Meg: We have the same dad, idiot!
Chris: Yeah, but mine's smarter!

Meg: There's no factory?
Stewie: Ha! Very good, fat man! We follow the Pied Piper of Hamsteak to the Gates of Oblivion, and look what it's brought us! We're finished! We're done! Game over, man! Game over!

(Meg tells Brian about her backup for the dance and how he already had plans)(scene cuts to Meg at the front of Jimmy's door)Meg: Hi Jimmy, umm I heard you didn't have a date to the dance and I was wondering if you would like to go with me..Jimmy: Oh....uhhh...I...uhh....h-hang on..(runs inside and closes the door)(two gun shots are heard firing in the house)Jimmy: (reopening door, crying) I'd love to go Meg, but.. (sniffs) .. I have to go to my little brother's funeral that night..

Meg: Everybody! Guess what I am?
Stewie: Hmm, the end result of a drunken back seat grope-fest and a broken prophylactic?

Meg: I'm going to the mall later, (Provocatively) maybe you can come and help pick out some underwear?
Brian: Uh, I don't think that's going to be a possibility...uh, I have...plans, um (Chris walks in) with Chris! Chris and I uh, have plans this afternoon.
Chris: We do?
Brian: Yeah, yeah we're doing that, thing. We're doing what you usually do on a Thursday afternoon.
Chris: Masturbate?
Brian: That's it, that's what we're going to do together.
Chris: Well, maybe back to back, but I got to tell ya, I'm not a hundred percent on this.

Meg: I miss Uncle Patrick.
Lois: Don't worry kids I promise we can visit him once a month.
Chris: We'll be his period.

Peter: (kicking the driver's seat in the car) I WANT APPLE JUICE!!!
Meg: (sighs) You wanna watch SpongeBob?
Peter: Yes! With apple juice.
(Meg pulls down a TV screen and Peter watches SpongeBob)

Meg: Chris, quit it! Mom! Chris put his foot on my side again!
Chris: I can't help it. I have these long dancer's legs.
Meg: Move it!
Stewie: Meg, stop your whining. Chris, stay on your own side. Lois, for God's sake, get off your ass and do some parenting!

Lois: So Meg, did any of the neighbors see Jeff come over?
Meg: Mom! Come one Jeff, let's go in other room.
Lois: Now Meg, no need to get so testes, uh testy. Nuts, I mean crap!

Lois: If you kids don't knock it off, we're not goin' to McDonald's after church.
Meg and Chris: MOM!
Peter: Don't worry. We're goin'. B-B-But you don't get the Supersize.
Chris: OH!
Peter: Okay, you can Supersize. But no apple pie!
Meg: Oh, come on!
Peter: Okay, you get an apple pie, but you can't blow on it

Genie: I am here to grant you three wishes.
Lois: Peter, three wishes. Oh this is so exciting.
Meg: I want a new hat
Chris: I want a new hat
Stewie: I want them to have new hats!

Family Guy Quotes

Aunt Margarite [on her video will]: Lois, you were always my favorite niece; I just knew you would find a wonderful man who would make all your dreams come true. But I was wrong.
Peter: And now you're dead. Score one for Peter

But now that you mention it, your face looks like a used condom.

Quagmire