Oh god how do you get pink-eye? This is got to be it!

Peter

Peter: I missed you Brian.
Brian: I missed you too Peter.
Peter: And now Im gonna go upstairs and pee in Meg's bed.
Brian: No, we're going to go pee in Meg's bed.
Peter: Good boy.

Brian: Well I don't know if I'd label myself a drinker. I know I like a cold beer after I mow the lawn.
Peter: There were three lies in that sentence.

Oh yeah 'cause you know him so well, shut your faaaaaace.

Stewie

Neil: Is this a nut free counter?
Chris: Uh I don't know, my dad's might have been on there at some point.

Stewie: Yes looks like someone's gone at him with a whip.
Brian: That is a perfectly valid way of saying that. Bravo master.
Stewie: Master? Aaand a surprisingly quick erection for Stewie.

Hey? You up? Guess where I have a crayon?

Stewie (seductively to a little girl at nap time in school)

Ugggh! This tastes like Ani DiFranco after a bike ride!

Quagmire (referencing an awful Korean Taco)

How do you think NBA players get all those chicks? They're all great cooks. Except Kobe Bryant. His secret is different.

Quagmire

God he must be the coolest fat guy in a train conductor's cap in the world!

Brian (referring to George R. R. Martin)

Tom Cruise: Nobody walks away from tiny Tom Cruise.
Stewie: Yeah, except for all three of your wives.

You know, it's times like this where I think if I didn't talk and you were a normal baby, we wouldn't have any of these problems.

Brian

Family Guy Quotes

Aunt Margarite [on her video will]: Lois, you were always my favorite niece; I just knew you would find a wonderful man who would make all your dreams come true. But I was wrong.
Peter: And now you're dead. Score one for Peter

But now that you mention it, your face looks like a used condom.

Quagmire