"Sexual Healing"

Cathy and Paul have problems in bed this week. But Rebecca helps them out.

  • 4.4 / 5.0
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"Musical Chairs"

Cathy doesn't secure a spot in a new clinical trial. As a result, it's time to dabble in the supernatural.

  • 4.3 / 5.0
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"Losing Patients"

Sean and Cathy have a major falling out on the season two premiere, while Cathy deals with disturbing visions of Marlene.

  • 4.6 / 5.0
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"Taking the Plunge"

On the first season finale, we learn about Cathy and her bee sting treatment. Read on for a complete recap.

  • 4.8 / 5.0
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"Everything That Rises Must Converge"

Cathy seeks alternative treatment this week. Viewers are also treated to a guest appearance by Liam Neeson.

  • 4.3 / 5.0
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"New Beginnings"

Paul takes the news of Cathy's cancer hard this week, but he ends up responding in the perfect, caring way. Elsewhere, Cathy leans troubling information about Marlene, while Rebecca and Sean break up.

  • 4.2 / 5.0
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"Divine Intervention"

Cathy learns something about Andrea when she visits her at home this week. In other storyline news, Sean and Rebecca call it quits.

  • 4.6 / 5.0
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"The Ecstasy and the Agony"

Cathy gets bad news from her doctor on this episode: she has NOT been accepted for a clinical trial. Elsewhere, Andrea and Adam get into a fight, while Paul discovers something important.

  • 4.7 / 5.0
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"Happy Birthday, Cancer"

This week's episode is title "Happy Birthday, Cancer." It features Cynthia Nixon as a guest star, along with Cathy's birthday.

"Two for the Road"

Sean learns about Cathy's news on this episode. Elsewhere, Adam throws up on Marlene's lawn after getting wasted.

  • 4.6 / 5.0
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The Big C Quotes

Sean: The last you could do is buy a damn Hybrid.
Cathy: The least you could do is take a shower.

Paul: Can we at least figure out what to tell Adam? Because right now, my story is: "Adam, your mom's a meanie!"