Marge [about Homer]: Is he okay?
Akira: He feels no pain. Oh I'm sorry, my English is not so good. I meant to say he feels only pain

This goes against every feminist bone in my body, but dad, can't you control your woman?

Lisa

Of all the crazy things I've ever done, this is the craziest and you're doing it!

Homer [to Marge]

I am not a scalper, I'm just a dude whose 200 friends did not show up

Ticket Scalper

Marge: Ultimate makes everything worse
Otto: Not frisbee!
Marge: Otto, don't you have a sack to hackey?

I know we saw awesome beatdowns tonight, but remember don't try this at home. Do it at the school yard, someplace where if you get hurt, we can sue. And not just them, but the school, the county, the state and that jackass Joe Biden

Homer [to Bart]

Groundskeeper Willie: Come on ya pansies, I've seen fiercer fights in parliament
Sideshow Mel: What is this, prime minister's question time?

I'm a Simpson, and a Simpson never gets up unless he's tried at least one easy thing

Bart

Milhouse: Maybe we can find an answer in this bookstore
Bart: Book stores don't have answers, the just have creepy guys sitting in easy chairs at the end of aisle ways

Bart: Mrs K, you have to get out of here. When was the last time you washed your hair?
Edna Krabapple: Hmm, two weeks ago...
Bart: Well, that's better than me, but still, you gotta get out

Marge: I'm worried about Mrs Krabappel
Bart: No worries, I heard in the old four square court she was doing great
Lisa: No one even plays four square anymore, they just gossip

Lisa: I thought you were studying the Lincoln-Douglas debates?
Bart: You mean the L-man, D-dawg flame wars?

The Simpsons Season 21 Quotes

Comic Book Guy: You are acceptable!
Homer: Great, would you like to see me naked?
Studio Exec: Oh, there's no nudity in this movie
Homer: What movie?

I played hardball with hollywood, the closest i will ever come to playing a sport in my life

Comic Book Guy