Chris: So did you get a lot of trim on the road?
Peter: Chris, that's wildly inappropriate

This shouldn't embarrass you, the size should embarrass you.

Lois [to Peter]

Says 'Glenn Quagmire.' But if you squint and imagine it says 'Peter Griffin,' it says 'Peter Griffin'!

Peter

Oh my god, look at you! You're more herpes than dog!

Stewie

Oh my god! Your mouth looks like the underside of a boat!

Teacher

Scumbag: Smells like this guy's already wet himself.
Peter: Don't flatter yourself--that was from this morning.

You've got herpes, too? This house is like backstage at a Whitesnake concert.

Stewie

Stewie: How long have you been there?
Chris: Long enough to know that you have herpes and do weird stuff with your teddy bear.
Stewie: HE does weird stuff; I just don't stop him.

Peter: Let me help you! I'm great at finding stuff. Last night, I found Lois's g-spot!
Lois: No, he didn't!
Peter: I didn't think she was home.

I'm gonna see which lobster I think deserves to die.

Chris

Donna: Oh Lois, I'm so glad to see Peter and Cleveland back together again.
Lois: Yeah, me too. Now Peter will have something to do besides flushing the toilet to Foghat's "Slow Ride."

That's the Riddler. He would make inquiries to set your mind a-jumble.

Cleveland

Family Guy Quotes

Aunt Margarite [on her video will]: Lois, you were always my favorite niece; I just knew you would find a wonderful man who would make all your dreams come true. But I was wrong.
Peter: And now you're dead. Score one for Peter

But now that you mention it, your face looks like a used condom.

Quagmire