(Stewie follows Chris while playing his funny beat on his tuba)
Chris: Cut it out!
(Stewie keeps playing)
Chris: I'm just trying to live my life!
(Stewie keeps playing)
Chris: No one taught me about carbs!
(Chris trips, Stewie makes a flatulence sound)

Cool, I don't have to go to school. I can just pee in my bed all day.

Instructor: Welcome to the Quahog maritime school Chris. Our curriculum consists of being on boats for long periods of time with men, just men, for many days at a time. Up on the deck with lots of men, or down in the galley with lots of men.
Chris: Is this some kind of pirate school?
Instructor: Well... a certain kind of pirate. Yes, we've been called that.
Chris: I don't know...
Stewie: Is there some kind of pre-school program?

Lois: So, do you think your school would be right for Chris?
School Guide: Oh, Absolutely. Quahog school for the deaf has great programs, both academic and athletic. In fact, your just in time for our Homecoming Pep Rally.
Guy: What are we gonna do to Lincoln!
Crowd: Kill them!
Guy: I can't hear you!
Crowd: Kill them!
Guy: I can't hear you!
Crowd: Kill them!
Guy: I can't hear you!
Crowd: Kill them!
Guy: I can't hear you!
Crowd: Kill them!
Chris: Lets just go.

Principal: I suppose there is one thing I could do to raise the school's test average.
Lois: Then do it!
Principal: Oh right, we'll drop the dumbest student we have. Chris Griffin is hereby expelled!
Chris: But if I leave now, I won't hear who is the dumbest kid in school.

Chris: Are you sure Aunt Carol won't mind us using her house?
Lois: She won't care Chris. She's off on her ninth honeymoon.
Peter: (laughing) When will it work for her?

Meg: Wow, look at this! I can't believe that Mrs. Bush kept all of these Planned Parenthood receipts.
Chris: Holy Cow! She's been scraped more times than a fisherman's knuckle!

Lois: Well, I got good news. I'm going to be the Church's new organist. (Both Brian and Meg talk simultaneously.)
Brian: Hey, hey, congrats.
Meg: Wow mom, that's great.
Chris: That means you'll play the organ.

(After Meg finishes typing on laptop.)
Chris: Meg, you are so full of crap. You're like those people who sit in Starbucks and publicly write on their laptops. (Scene with two guys typing on their laptops in Starbucks.)
Guy #2: Hey, getting some writing done there buddy?
Guy #1: Yeah, setting up in public so everybody can watch me type my big screenplay.
Guy #2: Me too. All real writers need to be seen writing otherwise what's the point, right?
Guy #1: You should totally write that down!
Guy #2: Okay, will you watch me?

Bill Clinton: All right, are you ready for another round of N.A.F.T.A
Lois Griffin: What does N.A.F.T.A. mean?
Bill Clinton: 'Nother Afternoon of F****** That Ass!

(Chris and Quagmire are on the couch with a calculator, Chris is typing in numbers)
Quagmire: Okay, now add twenty.
Chris: Okay.
Quagmire: Now multiply it by four.
Chris: Okay.
Quagmire: Now what do ya got?
Chris: Eight thousand and eight.
Quagmire: And what does eight thousand eight look like on a calculator?
Chris: Oh, Boob!
Quagmire: Boob! Yeah! Alright, alright, alright, Boob!
Chris: What if we had two calculators and we put em next to each other?
Quagmire: Huh! Yes, yes, yes, find one, yes.

Lois: Chris, what happening to the couch?
Chris: Dad dragged it out on the lawn because he said "that's what rednecks do!"

Family Guy Quotes

Aunt Margarite [on her video will]: Lois, you were always my favorite niece; I just knew you would find a wonderful man who would make all your dreams come true. But I was wrong.
Peter: And now you're dead. Score one for Peter

But now that you mention it, your face looks like a used condom.

Quagmire