Lois: Oh, my God! You can only play the piano when you're drunk!
Peter: Now that's not true! I can also vomit, fall down and make dirty calls to your sister when I'm drunk!

Lois: Oh, I haven't been on a college campus in years. Everything seems so different.
Stewie: Really? Perhaps if you laid on your back with your ankles behind your ears that would ring a few bells

My days in college were so exciting. This one time, the national guard came and shot some of my friends

Lois: It's time to call this whole thing off. Nobody's on our side.
Peter: Are you nuts? Look at all these telegrams. "Nice going, Libya." "You da man, North Korea." "Great job, Iraq." Iraq, Lois! You know what? I'm gonna invite a few of these fellas over for a party

Lois: I hate what you become! Why don't you go back to that doctor and tell him to suck the fat out of your head?
Peter: Maybe I will, and then I'll put it on my feet and skate on Paul Bunyan's skillet to cook his flapjacks.
Lois: That doesn't make any sense!
Peter: It doesn't have to, Lois, I'm beautiful

Lois: Did you paste your picture over our wedding portrait?
Peter: Yeah, I think it looks better.
Lois: You pasted it over mine.
Peter: Yeah, I think it looks better

Lois: Peter, did you get a new buttocks?
Peter: I had to. My old one had a crack in it.

Lois: Jump in, sweetie! The turtle will protect you!
Stewie: I'm supposed to entrust my life to a turtle?! Nature's "D" student?

Lois: Okay, meatloaf for us, and a very special, very delicious, steamed vegetable dish for Chris.
Chris: Ohhh. It tastes like a monkey. A monkey that's past it's prime

Lois: Together we can do anything: face any foe, overcome any obstacle.
Peter: Yeah, climb any mountain, rent any video, dial any phone. And not just our phone, Lois, other people's phones. Decent phones, God-fearing phones, phones that everybody else gave up on, but we knew better because we were a team!
Brian: What the hell are you talking about?

Lois: I just wish my opinion mattered to you.
Peter: Well, the important thing is, it matters to you, and that's the greatest gift of all

Lois: Peter, this car has dents in it, and it's got a cardboard steering wheel.. And look, there's no engine! It just has a drawing of an engine!
Car salesman: But it only had one previous owner...James Bond!
Peter: I'll take it!

Family Guy Quotes

Aunt Margarite [on her video will]: Lois, you were always my favorite niece; I just knew you would find a wonderful man who would make all your dreams come true. But I was wrong.
Peter: And now you're dead. Score one for Peter

But now that you mention it, your face looks like a used condom.

Quagmire