Lois: They might be very nice people.
Peter: Very nice people, yeah that's what they always say. Then you open up the septic tank and BAM, skeleton city

Mr. Weed: Unfortunately, Johnson isn't here to pitch today, his wife is in labor.
Peter: Oh what, is the baby coming out of him? Jeez, I'll pitch

Joe: Say, do you have a screwdriver I can borrow?
Peter: Man, you neighbors are like viruses, starts with a screwdriver, then before you know it you're using my supermarket, dry cleaner, even my postman

Peter: Boy, I got myself into a real situation, didn't I? But don't worry, I've got a plan to get us out of this!
Brian: Oh, good, I was afraid you were just going to improvise.
Peter: Oh, well actually I was gonna use the little girl as a human shield and run like hell! But uh, yeah, improvise. That'll be easier on my back

Old Woman: Help! Someone just stole my purse!
Peter: Who cares, I don't even know you

Where am I gonna find a ringer as strong as Guillermo? One time, I walked into the locker room; I swear he was bench-pressing Mr. Weed

Jeez Lois, I just spent all morning on a boat with my friends drinking beers, telling jokes, and screwin' around. How 'bout a little me time?

Man: Wow, Lois Griffin, Hey, I love your act! Nice melons.
Peter: Now listen pal!
Lois: Peter, I'm holding melons.
Peter: Oh.
Man: And her hooters aint bad either.
Peter: Now hold on a second.
Lois: Peter! I'm holding hooters!
Peter: Oh, sorry.
Man: No problem.... Your wife's hot
Peter: Alright that's it

Peter: I know you cant understand what I'm going through, Lois. I mean all the stuff that makes you happy, you know, like cooking and cleaning - it's alright here in the house just waiting for you. You are one lucky...
Brian: Uh, uh stop. Now

[Stewie stumbles up to Lois...]
Stewie: Hello mother, care to partake in your oh so exhilarating games of Peek-A-Boo?
Lois: Oh my god, my baby's drunk!
Peter: No I'm not, what, oh him? Oh yeah, he's a real light weight

Brian: Something troubling you Peter?
Peter: Oh no, nothing. Just all of my friends are eye-humping my wife.
Brian: Well if I were you, I'd keep an eye on her. Then again I'm the jealous type

I feel just like Tim Allen. I build stuff and I have a criminal record

Family Guy Quotes

Stewie: (Comes into the bedroom) Lois! Lois! Lois! Lois! Lois! Lois! Mom! Mom! Mom! Mommy! Mommy! Mommy! Mama! Mama! Mama! Ma! Ma! Ma! Ma! Mum! Mum! Mum! Mum! Mummy! Mummy! Mumma! Mumma! Mumma!
Lois: What!?
Stewie: Hi! (Giggling and running out of the room)

Hi, I'm Wilford Brimley and I have diabetes. It hurts me to pee and it causes me to be short with my family. I can't sleep at night. The other day I stubbed my toe and took it out on the dog. And two weeks ago I ran out of vanilla ice cream and struck my wife. Then I find out my wife has been dead for six years. Who the hell did I hit?

Wilford Brimley