Chris: I think I saw of her nipples.
Lois: Chris that's a terrible word. Nipple. I'll chalk that up to the heat mister

Stewie: You, you seem to know all the players in this poorly acted farce. What do they call that one?
Chris: That's Meg dude. You know that.
Stewie: Meg! You vile, smelly girl. You're not to touch any of my things. Do you understand me? Dirty, dirty girl

All Brian's ever wanted is the same respect he gives us. Well, that and snausages. He's freakin' mental for those snausages!

Peter

Meg: Ugh, it' so hot out there.
Griffins: How hot is it?
Meg: I don't know. Like around 98, 99.
Peter: I don't get it

Peter: Sometimes we all need a second chance. Sometimes we all need to forgive!
Chris: I stole ten dollars from Meg's room.
Meg: I stole ten dollars from mom's purse.
Lois: I've been making counterfeit ten dollar bills for years

Brian: Things can never go back to the way they were! Not after the way I was treated! Not after the things I've seen!
Chris: What did you see? Was it breasts?

Meg: Chris, you're hogging up all the fans.
Chris: Well, you're hogging up all the... ugly!

Carnie: Step right up, step right up! You won't believe your eyes. Step right up and see the amazing half man, half clam.
Peter: What a ripoff, it's just Kim Cattrall sitting Indian style

Thanks honey, say hi to your husband. [device on his belt beeps] Oh, I've got AIDS again, better take my NyQuil Cold, Flu and AIDS. [takes pill] All gone!

Quagmire

Gosh Brian, I sure hope this next leap, will be the leap home

Stewie

Take your stinkin' paws off me you damn dirty dog

Stewie

How the hell am I going to break this to Lois? If she finds out I got fired for drinking, she's going to blame me!

Peter

Family Guy Quotes

Aunt Margarite [on her video will]: Lois, you were always my favorite niece; I just knew you would find a wonderful man who would make all your dreams come true. But I was wrong.
Peter: And now you're dead. Score one for Peter

But now that you mention it, your face looks like a used condom.

Quagmire