Alan: Heard any good jokes lately?
Charlie: Yeah. Two brothers are sitting on a couch and one of them says heard any good jokes lately and the other one, get this, lights him on fire.

Dr: What do you consider being truly intimate with a woman?
Charlie: Not using a condom?

I saw your commercial for the shake weight. My brother does basically the same thing in the shower every night. He has absolutely no muscle definition in his arms.

Lady: Oh my god, you threw up on my baby!
Charlie: To be fair, I don't think the carrots were mine.

We all want the shining red apple, but sometimes we got to settle for what's on the lower branch, or in some cases we take what's lying on the ground

And you call yourself a drummer. Keith Moon is vomitting in his grave.

Charlie: Sure you don't want a drink?
Alan: Nah, when I'm depressed alcohol just makes me feel worse
Charlie: Yeah, same. The trick is to drink past that. It's not a sprint, it's a marathon

Alan: What's the forecast?
Charlie: High tonight, low tomorrow, 100% chance of hangover.

Jake: Hey, Uncle Charlie, you want to dance with me?
Charlie: Hey, Jake, want to live in a foster home?
Jake: Sometimes.
Charlie: Don't sass me, boy. I'll take the switch to you.

Jake: You're cheap.
Alan: I'm not cheap. I'm broke. There's a difference.
Charlie: He was cheap long before he was broke.

The day you start accepting limitations is the day you start dying, and I am not dying, my friend. I am living life to the fullest. Now, if you'll excuse me, I'm gonna go throw up and take a nap

Charlie: Tell you what. I'll trade you, site unseen, my mom for yours
Chelsea: Charlie..
Charlie: I'll even throw in Alan and a couple of Omaha Steaks

Two and a Half Men Quotes

Charlie: I understand you teachers are sadly underpaid.
Miss Tuttle: That's very true.
Charlie: Well, I'd like to do my part. Can I buy you dinner?

Yeah, hi. I'm watching your commercial cash for gold and you just showed a woman selling her wedding ring for $500. No, I don't want to sell gold, I want to meet her. She's hot and we know her marriage isn't working out.