"Sweet Surrender"

Izzie plays wedding planner to take her mind off her treatment, while Callie introduces Arizona to her disapproving father, and Owen seeks help for his PTSD.

"Elevator Love Letter"

Derek returns to the OR after his meltdown, while Izzie's condition requires her to undergo an operation of her own.

"Stand By Me"

Cristina and Izzie debate what do to next, while Mer attempts to get Derek out of the woods and back to work.

"I Will Follow You Into the Dark"

Derek decides to quit, but Meredith refuses to give up on him. Bailey and the Chief continue to bicker, while Izzie's interns discover something unsettling.

"An Honest Mistake"

Derek and Addison square off yet again - this time with a patient's life in the balance. Bailey, meanwhile, is stunned by Richard's recommendation letter.

"Before and After"

Addison, Naomi and Sam rush to Seattle Grace with Archer and reunite with old friends Derek and Mark. Izzie employs her fellow doctors in a medical game. Owen runs into someone from his past.

"Beat Your Heart Out"

In "Beat Your Heart Out," Derek searches for the best way to pop the question to our girl, while Little Grey wants to go public with Big Sloan.

"Stairway to Heaven"

As a patient's condition becomes more and more dire, Bailey becomes more and more desperate to do something - anything - to save him.

"Sympathy for the Devil"

Death row inmate William is still around and he's shaking things up, while Derek's mother comes to Seattle Grace and meets Meredith for the first time.

"Wish You Were Here"

Grey's Anatomy returns from its holiday hiatus with its 11th episode of Season Five.

Grey's Anatomy Quotes

Arizona: Oh my God! I mean, I understand why you're into her. She's hot. Wait, she likes you?
Nathan: What? I mean, I'm going to try not to be offended at that.
Arizona: No, no, no. It's just that Derek was--Derek was epic for her. They were the great love story. I mean, that girl's heart beat for Derek Shepherd. It just...it never occurred to me that she would ever be with anyone else. He was perfect. He was everything. That man turned her world. It...I spooked you. Don't be spooked.

Did you say it? 'I love you. I don't ever want to live without you. You changed my life.' Did you say it? Make a plan. Set a goal. Work toward it, but every now and then, look around; Drink it in 'cause this is it. It might all be gone tomorrow."

Meredith (closing voiceover)